
People are generally most
familiar with the movement-oriented, or “motor” symptoms of
Parkinson's disease, as they are the most evident external evidence
of the disease. These symptoms, which are also called
the "cardinal" symptoms of PD, can be remembered by using the
acronym “TRAP”:
(T)remor – usually a resting
tremor, often in the hands, arms, legs, torso, or lips and
face. The tremor tends to be relatively slow, about 4-6
cycles per second, and often shows a “pill-rolling” movement in the
hands and fingers.
(R)igidity – muscular
stiffness and tightness, often displaying a “start and stop” jerky
motion called “cogwheel rigidity” when a limb is manually
moved.
(A)kinesia or bradykinesia –
lack of movement or extreme slowness in movement.
(P)ostural instability –
limping, shuffling gait, or balance problems, often resulting in
falls.
Lack of facial expression is also
a common characteristic resulting from the four cardinal
symptoms.
Also important are the
non-movement symptoms of PD, sometimes called "non-motor" or
"dopamine non-responsive" symptoms. These common symptoms can
have a major impact on people with PD. For example, cognitive
impairment, ranging from mild memory difficulties to dementia, and
mood disorders, such as depression and anxiety, occur frequently,
particularly in people with Parkinson’s (PWPs) with later
onset. Also common are sleep difficulties, loss of sense
of smell, constipation, speech and swallowing problems, unexplained
pains, drooling, and low blood pressure when standing.
Not all PWPs experience the same
symptoms, have the same rate of progression, or respond to
treatment the same way. These facts lead to the common
saying, “when you’ve seen one person with Parkinson’s, you’ve seen
one person with Parkinson’s.” Each case tends to be
different.
